Article Title Essay Example | Topics and Well Written Essays - 500 words

Article Title - Essay Example The article reveals three separate research studies conducted to track the origins of cancer cells in the brain, gut and skin using genetic markers as labels. The studies conducted by Luis Parada and Hans Clevers on brain and gut cancers respectively used genetic labels to mark healthy adult stem cells which had the potential to develop into tumors and analyzed whether the newly formed cancer cells contained the same labels as their predecessors. In the experiment conducted by Parada on glioblastoma, the tumors also contained some unlabelled cells which had also originated from the labeled cells which relapsed following chemotherapy. However, when the labeled cells were targeted using chemotherapy the glioblastoma underwent significant shrinkage. Clevers and his team used drug-inducible genetic markers which when activated caused the cells carrying the marker to fluoresce in one of the four colors. When a second dose of the drug was injected the initially fluorescing cells gave rise to a new set of cells that fluoresced with a different color thus supporting the hypothesis that cancer stem cells give rise to new tumor cells. In the experiment involving the skin tumor conducted by Cedric Blanpain, individual tumor cells were labeled and when tracked these either gave rise to a small cell lineage before diminishing or continued to produce more cells. Thus the study provided a strong experimental evidence for the existence of cancer stem cells and further research involved relating these tracked cells with those of the putative cells which have been found from transplantation studies. The photosynthetic ability of aphids using the carotenoid pigment which they synthesize is explored in the Nature article, â€Å"Photosynthesis-like process found in insects†. Aphids and another possible creature namely the two-spotted

The Sign of Four and Murder on the Orient Express Research Paper

The Sign of Four and Murder on the Orient Express - Research Paper Example When you ask for the name of the most famous of detectives from literary history many people would probably say the clever, remarkable and rational 19th century British detective, Sherlock Holmes, created by Sir Arthur Conan Doyle, and who was the basis for a number of Doyle’s novels. Another famous detective, that might rank a close second, popular among literary circles is Hercule Poirot, the rather quirky Belgium detective dreamt up by writer Dame Agatha Christie. These two authors set precedents in plot courses, mystery literature, developed classic characters, and earned them, both a large amount of notoriety and fame. The best way to understand these main characters is to compare and contrast their similarities and differences in two specific works: â€Å"Sign of Four† by Doyle and â€Å"Murder on the Orient Express† by Christie. Through these means we can compare and contrast their story styles and themes, their development of their protagonists, and the a uthors themselves. Arthur Conan Doyle was born in Edinburgh, Scotland in May of 1859 to a strict Irish-Catholic family. Doyle’s father had little success in life and was struggled with alcoholism. His mother was an educated woman who enjoyed reading and telling stories.